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Neurointervention 2008;3(2):69-74.
Intraarterial Thrombolysis for Central Retinal Artery Occlusion.
O Ki Kwon, Chul Kyu Jung, Kyo Jun Whang, Byung Chul Kim, Eun A Jung, Moon Hee Han
1Department of Neurosurgery, Clinical Neuroscience Center, Seoul National University Bundang Hospital, Korea. kwonoki@korea.com
2Department of Radiology, Clinical Neuroscience Center, Seoul National University Bundang Hospital, Korea.
3Department of Radiology, Seoul National University Hospital, Korea.
Central retinal artery occlusion (CRAO) typically causes severe and permanent visual loss in the affected eye and vision does not recover in 90% of the patients. It is believed that it occurs by occlusion of the central retinal artery with small emboli from atherosclerotic plaque of internal cerebral artery. Various methods have been introduced to recanalize the occluded artery and remove emboli but considered to fail except thrombolytic therapy. Retina is a part of the brain so basically CRAO is corresponding to acute occlusion of intracerebral artery and retinal ischemia is to cerebral stroke. Accordingly rapid procedure within therapeutic time window, choosing appropriate drugs and doses, reducing hemorrhagic and ischemic complications associated with neurovascular intervention is very important. However, clinical significance of CRAO is much different from that of acute cerebral arterial occlusion, therefore, neurointerventionists should perform this procedure within appropriate range of safety.
Key Words: Central retinal artery occlusion; Intraarterial thrombolysis
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